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In conclusion, we have provided evidence indicating that GLP-1 and PYY release in response to TGR5 activation is mediated via the Gs/cAMP/PLC/Ca 2+ pathway and both endogenous and exogenous H 2 S inhibit TGR5-mediated GLP-1 and PYY release

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Quantification of mitochondrial superoxide was similarly executed except that the samples were stained with 5 M MitoSox TM Red (Thermo Fisher Scientific)

Fat storage patterns start changing